Name of the Probiotics Drugs
- Lactobacillus sp.
- Bifidobacterium
- Saccharomyces boulardii
1.Lactobacillus sp.
| Lactobacillus sp. |
| Availability Lactobacillus: 1-2 capsules/day PO 1-10 billion CFU’s/day PO divided TID-QID 8 oz yogurt BID |
Mechanism of Action
Restores normal bowel flora that inhibit growth of harmful bacteria; stimulates local immunity; promotes water reabsorption in colon
Contraindications
Immunocompromised patients.; GI wall perforation
2.Bifidobacterium
| Bifidobacterium |
| Availability 1 capsule (4 mg) PO daily |
Mechanism of Action
Restores normal bowel flora that inhibit growth of harmful bacteria; stimulates local immunity; promotes water reabsorption in colon
Contraindications
- Hypersensitivity
- Immunocompromised patients
- GI wall perforation
Cautions
- If on a lactose-free diet, talk with healthcare practitioner; some products have lactose
- If you have high blood sugar (diabetes), check labels closely; some products have sugar
- Tell doctor if pregnant or planning on getting pregnant; discuss benefits and risks of using probiotic capsules while pregnant
- Tell healthcare practitioner if breast-feeding; discuss possible risks to the baby
3.Saccharomyces boulardii
| Saccharomyces boulardii |
| Availability 1 capsule/packet PO BID |
Mechanism of Action
Restores normal bowel flora that inhibit growth of harmful bacteria; stimulates local immunity; promotes water reabsorption in colon
Contraindications
- Patients with a central line
- Yeast allergy
- Hypersensitivity to product or excipients
Cautions
- Use with caution in patients with lactose intolerance; some products may contain lactose
- Use with caution in immunocompromised patients as product contains live bacteria; fungemia reported in premature infants
- Do not open packets or capsules when in the vicinity of patients with central lines; change gloves after handling product to avoid transfer into central lines of patients
- Dietary supplements do not have safety or efficacy review by the FDA; conclusive evidence to support widespread use of product in the treatment of diarrhea is lacking
- Potentially significant interactions possible; frequency, dose adjustment, or monitoring may be necessary
REFERENCES
- Robert Kizior, Keith Hodgson, Saunders Nursing Drug handbook,1st edition 2024, Elsevier Publications. ISBN-9780443116070
- McGraw Hill- Drug Handbook, Seventh Edition, 2013, McGraw Hill Education Publications,9780071799430.
- April Hazard, Cynthia Sanoski, Davi’s Drug Guide for Nurses -Sixteenth Edition 2019, FA Davis Company Publications,9780803669451.
- Jones and Bartlet, Pharmacology for Nurses, Second Edition, 2020, Jones and Bartlet Learning Publications, ISBN 9781284141986.
- Nursebro.com, Search – Nursebro
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