Hand Hygiene: Best Practices for Nurses in 2025

Infection COntrol

Introduction

Hand hygiene stands as the single most effective measure for preventing healthcare-associated infections (HAIs) and safeguarding both patient and healthcare worker health. For nurses, who are in constant contact with patients and their environments, adherence to proper hand hygiene practices is not merely a personal responsibility but a professional and ethical imperative.

Hand Hygiene

Why Hand Hygiene Matters in Nursing

Nurses are at the frontline of patient care, providing a wide range of services from wound dressing and medication administration to intimate personal care. Each of these activities carries a risk of transmission of infectious agents if adequate hand hygiene is not maintained. The consequences of poor hand hygiene can be grave, including the spread of multi-drug resistant organisms (MDROs), increased patient morbidity and mortality, prolonged hospital stays, and elevated healthcare costs.

Hand hygiene is not only about self-protection but also about breaking the chain of infection to protect vulnerable patients. The World Health Organization (WHO) estimates that hundreds of millions of patients are affected by HAIs each year worldwide, with the majority being preventable through simple interventions such as hand hygiene.

Mechanisms of Infection Transmission in Healthcare

Hospital environments are complex ecosystems where pathogens can be transmitted through direct contact (person-to-person), indirect contact (via contaminated surfaces or equipment), droplets, or even airborne routes. The hands of healthcare workers, particularly nurses, often serve as the primary vehicle for cross-transmission of pathogens between patients, surfaces, and themselves.

Common pathogens transmitted via hands include:

  • Staphylococcus aureus (including MRSA)
  • Clostridioides difficile
  • Escherichia coli
  • Norovirus
  • Influenza viruses
  • Respiratory syncytial virus (RSV)

The risk is heightened in settings involving immunocompromised patients, such as intensive care units, oncology wards, and neonatal units. Nurses working in these areas must be particularly vigilant about hand hygiene practices.

Evidence Supporting Hand Hygiene

Numerous studies and systematic reviews have unequivocally demonstrated that improved hand hygiene compliance leads to significant reductions in HAIs. For example, interventions that increase hand hygiene among healthcare workers have been shown to reduce rates of MRSA and other infections, contributing to better patient outcomes and reduced healthcare expenditure.

The WHO’s “Clean Care is Safer Care” campaign and the Centre for Disease Control and Prevention (CDC) both prioritise hand hygiene as a cornerstone of infection prevention and control (IPC) strategies. In India, the Ministry of Health & Family Welfare and the Indian Council of Medical Research (ICMR) have also issued guidelines that reinforce the critical nature of hand hygiene in clinical settings.

Barriers to Hand Hygiene Compliance

Despite widespread awareness, hand hygiene compliance among nurses often falls short of ideal levels. Common barriers include:

  • Workload and Time Constraints: High patient loads and staff shortages can make it difficult for nurses to perform hand hygiene as frequently as required.
  • Skin Irritation: Frequent washing with soap and water or alcohol-based hand rubs can cause dryness and dermatitis.
  • Lack of Resources: Inadequate availability of hand hygiene products (such as hand sanitisers, soap, and clean towels) can impede adherence.
  • Insufficient Training: Gaps in knowledge about the importance and correct technique of hand hygiene.
  • Cultural and Behavioural Factors: Perceptions that hand hygiene is not always necessary, especially when gloves are used, or during low-risk procedures.
  • Environmental Factors: Poorly designed sinks, inconveniently located dispensers, or lack of reminders.

Key Moments for Hand Hygiene: The “Five Moments”

The WHO’s “Five Moments for Hand Hygiene” provides a clear framework for when nurses must perform hand hygiene:

  1. Before touching a patient
  2. Before clean/aseptic procedures
  3. After body fluid exposure/risk
  4. After touching a patient
  5. After touching patient surroundings

These moments are designed to interrupt the transmission of pathogens at critical points in patient care.

Best Practices for Improving Hand Hygiene Compliance

Improving hand hygiene compliance among nurses requires a multifaceted approach that addresses individual, organisational, and environmental factors. The following best practices are recommended:

1. Education and Training

Regular, evidence-based training sessions should be conducted for all nursing staff, focusing on:

  • The importance of hand hygiene and its impact on patient outcomes
  • Correct handwashing and hand-rubbing techniques
  • Situational awareness regarding the “Five Moments”
  • Updates on new guidelines and emerging pathogens

Training should be interactive, incorporating demonstrations, return demonstrations, and scenario-based learning. In Indian settings, training in local languages and with culturally relevant examples can enhance understanding and retention.

2. Ensuring Accessibility of Hand Hygiene Products

Hand hygiene products must be readily available at the point of care. This includes:

  • Alcohol-based hand rub dispensers at every bedside
  • Well-maintained sinks with running water and soap
  • Disposable paper towels or air dryers
  • Hand cream or lotion to prevent skin irritation

In resource-constrained settings, creative solutions such as portable hand sanitiser bottles and mobile handwashing stations can be considered.

3. Leadership and Organisational Support

Hospital leadership must demonstrate commitment to hand hygiene by:

  • Allocating budget for hand hygiene supplies
  • Setting clear policies and expectations
  • Modelling good hand hygiene behaviour
  • Recognising and rewarding compliance among staff

Nurse leaders and infection control teams should conduct regular audits and provide constructive feedback to staff.

4. Monitoring and Feedback

Hand hygiene compliance should be regularly monitored using direct observation, electronic monitoring systems, or self-reporting tools. Data should be transparently shared with staff, and positive reinforcement provided for improvements.

Feedback mechanisms might include:

  • Monthly or quarterly compliance reports
  • Visual reminders (posters, badges, digital displays)
  • Peer-to-peer feedback and encouragement
5. Addressing Skin Care

To mitigate skin irritation, hospitals should provide hypoallergenic hand hygiene products and moisturisers. Nurses should be educated about proper skin care and encouraged to report any skin problems promptly.

6. Promoting a Culture of Safety

Creating a culture where hand hygiene is valued and prioritised requires:

  • Empowering nurses to remind each other about hand hygiene without fear of retribution
  • Embedding hand hygiene in the organisational mission and values
  • Celebrating “Hand Hygiene Day” or similar events to maintain enthusiasm
7. Use of Technology

Technological solutions can enhance compliance by:

  • Installing sensor-based dispensers that track usage
  • Implementing mobile apps for training and reminders
  • Using electronic badges or wearables that prompt hand hygiene at key moments

While these may be more feasible in well-resourced hospitals, even basic SMS reminders can be effective in Indian settings.

8. Adapting Strategies to Local Context

In India, strategies must reflect local realities, such as high patient loads, infrastructure challenges, and cultural attitudes. Involving nurses in the design and implementation of hand hygiene initiatives ensures relevance and sustainability.

Hand Hygiene Techniques: Soap and Water vs. Alcohol-Based Hand Rubs

Nurses should be familiar with the correct techniques for both handwashing and hand-rubbing:

  • Handwashing with soap and water: Recommended when hands are visibly soiled or after contact with bodily fluids. Steps include wetting hands, applying soap, scrubbing all surfaces for at least 20 seconds, rinsing, and drying thoroughly.
  • Alcohol-based hand rubs: Suitable for routine decontamination when hands are not visibly dirty. Apply enough product to cover all surfaces and rub until dry (20-30 seconds).

Hand hygiene should be performed before and after glove use, as gloves are not a substitute for clean hands.

Special Considerations

In healthcare settings face unique challenges, including overcrowding, limited resources, and high burden of infectious diseases. Strategies to improve hand hygiene compliance must therefore be pragmatic and resource-sensitive.

Some practical tips include:

  • Using cost-effective hand rub formulations recommended by WHO
  • Engaging local champions and nurse leaders to promote hand hygiene
  • Leveraging community health workers and primary care nurses to extend hand hygiene education beyond hospitals
  • Incorporating hand hygiene into nursing curricula and induction programmes

The Role of Nurses as Change Agents

Nurses are not only practitioners but also role models and educators. By consistently practising and advocating for hand hygiene, nurses can influence colleagues, patients, and visitors. Their leadership is critical in embedding hand hygiene into the daily routine of healthcare delivery.

Nurses can lead by:

  • Demonstrating correct hand hygiene at every opportunity
  • Encouraging a non-punitive environment for reporting lapses
  • Participating in quality improvement initiatives
  • Educating patients and families about the importance of hand hygiene

Measuring Success and Sustaining Improvements

Improvements in hand hygiene compliance should be measured not just by observation but also by tracking infection rates, staff satisfaction, and patient outcomes. Sustaining high compliance requires ongoing commitment, regular retraining, and adaptation to new challenges such as emerging infectious diseases (e.g., COVID-19).

Celebrating milestones, sharing success stories, and involving all members of the healthcare team are essential for maintaining momentum.

REFERENCES

  1. CDC, Clinical Safety: Hand Hygiene for Healthcare Workers, February 27, 2024, https://www.cdc.gov/clean-hands/hcp/clinical-safety/index.html
  2. Martos-Cabrera MB, Mota-Romero E, Martos-García R, Gómez-Urquiza JL, Suleiman-Martos N, Albendín-García L, Cañadas-De la Fuente GA. Hand Hygiene Teaching Strategies among Nursing Staff: A Systematic Review. Int J Environ Res Public Health. 2019 Aug 22;16(17):3039.
  3. Bogaert, C. (2025). Hand Hygiene: A Comprehensive Approach for Nurses. In: Oomen, B., Gastaldi, S. (eds) Principles of Nursing Infection Prevention Control. Principles of Specialty Nursing. Springer, Cham. https://doi.org/10.1007/978-3-031-84469-0_12
  4. WHO, Hand Hygiene, https://www.who.int/teams/integrated-health-services/infection-prevention-control/hand-hygiene

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